Catheter‐directed contrast‐enhanced coronary MR angiography in swine using magnetization‐prepared True‐FISP

Abstract
Contrast‐enhanced (CE) coronary magnetic resonance angiography (MRA) following intraarterial (IA) injection of contrast agent was compared using two sequences in swine: magnetization‐prepared fast imaging with steady‐state precession (True‐FISP), and magnetization‐prepared fast low‐angle shot (FLASH). Thick‐slice projection images were acquired with submillimeter in‐plane spatial resolution (0.9 × 0.8 mm2). The magnetization‐preparation scheme provided a clear delineation of the major coronary arteries with excellent background suppression. The True‐FISP acquisition resulted in an increase in signal‐to‐noise ratio (SNR) and contrast‐to‐noise ratio (CNR) by approximately a factor of 2 over FLASH (P < 0.05). Magnetization‐prepared True‐FISP is a promising technique for catheter‐directed CE thick‐slice projection coronary MRA. Magn Reson Med 50:1317–1321, 2003.