Hemodynamics of the Spleen in Banti's Syndrome
- 1 January 1967
- journal article
- research article
- Published by Tohoku University Medical Press in The Tohoku Journal of Experimental Medicine
- Vol. 93 (3) , 199-217
- https://doi.org/10.1620/tjem.93.199
Abstract
By means of a dye dilution method using Indocyanine green as an indicator, measurements of splenic blood flow and circulation time were carried out on control and ischemic spleens in the dog and on spleens of clinical cases of Banti''s syndrome. Splenic blood volume, vascular resistance and O2 consumption were calculated from the splenic blood flow and circulation time. Blood flow of the ischemic spleen of the dog was increased, compared to the control. In human subjects, total control splenic blood flow was approximately 300 ml/min. It was markedly increased in all cases of Banti''s syndrome. Splenic blood flow/gm tissue, however, was decreased in this syndrome. Concerning the splenic blood volume, resistance and circulation time, there were obvious differences between the control and diseased spleens. Total O2 consumption of the Banti spleen was 3-6 times greater than that of the control. Oxygen con-sumption/gm tissue, however, was markedly decreased. The splenic tissue in Banti''s syndrome was probably in a hypoxic state, which might play a role in the pathogenesis of this syndrome.This publication has 12 references indexed in Scilit:
- Regional Blood Flow by Fractional Distribution of IndicatorsAmerican Journal of Physiology-Legacy Content, 1958
- Effects of Adrenergic and Cholinergic Drugs on Splenic Inflow and Outflow Before and During Adrenergic BlockadeAmerican Journal of Physiology-Legacy Content, 1957
- Limitations of the Continuous Infusion Method for Measuring Cardiac Output by Dye DilutionAmerican Journal of Physiology-Legacy Content, 1953
- Measurement of Flow in Straight Tubes by Means of the Dilution TechniqueAmerican Journal of Physiology-Legacy Content, 1953
- Hepatic Circulation in Cirrhosis of the LiverCirculation, 1952
- Direct Splenic Arterial and Venous Blood Studies in the Hypersplenic Syndromes Before and After EpinephrineBlood, 1951
- THE OXYGEN CONSUMPTION OF THE NORMAL AND THE DISEASED HUMAN KIDNEY 1Journal of Clinical Investigation, 1949
- THE SIMULTANEOUS TRANSPORT OF T-1824 AND RADIOACTIVE RED CELLS THROUGH THE HEART AND LUNGSAmerican Journal of Physiology-Legacy Content, 1946
- Spleen studiesI. Microscopic observations of the circulatory system of living unstimulated mammalian spleensThe Anatomical Record, 1936
- STUDIES ON THE CIRCULATIONAmerican Journal of Physiology-Legacy Content, 1932