99mTc-Pyrophosphate Imaging in Acute Pericarditis: A Clinical and Experimental Study

Publisher Website
Google Scholar
Abstract
Patients (15) with clinical and ECG features of acute pericarditis underwent myocardial scintigraphy using 99mTc-pyrophosphate [PYP]. All had normal images. In 5 additional patients with acute pericarditis and evidence of ischemic heart disease, 99mTc-PYP images showed focal abnormalities in 2 patients and equivocal findings in 2. Serial myocardial radionuclide images were obtained 2-18 days after induction of pericarditis in 8 dogs; all images were normal. No stainable tissue Ca was demonstrated histochemically in the pericardium or myocardium of these dogs. 99mTc-PYP myocardial radionuclide images are apparently normal in acute pericarditis in the absence of ischemic heart disease.