Coronary Artery Calcium Score and Risk Classification for Coronary Heart Disease Prediction

Top Cited Papers
Open Access
Abstract
The coronary artery calcium score (CACS) has been shown in large prospective studies to be associated with the risk of future cardiovascular events.1-4 Recent data from the Multi-Ethnic Study of Atherosclerosis (MESA), a population-based cohort of individuals without known cardiovascular disease, found that a CACS greater than 300 was associated with a hazard ratio for future coronary heart disease (CHD) events of nearly 10.4 In addition, including CACS in a prediction model based on traditional risk factors significantly improved the prediction of future CHD events.