Alterations of Lipogenesis in the Intact Chick by Dietary Malonic Acid.

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Abstract
Summary Biotin deficiency in intact chicks resulted in lower total carcass fatty acid deposition and altered fatty acid composition as compared to normal chicks. Dietary malonic acid stimulated total fatty acid deposition in the carcass of biotin-deficient chicks but did not alter the fatty acid composition of the carcass. In normal chicks, malonic acid had no effect on total fatty acid deposition but altered fatty acid composition such that it approached the composition of deficient chicks. Growth and biotin-deficiency dermatitis were unaffected by malonic acid in deficient chicks, but malonic acid depressed the growth of normal chicks.