Preferred Microtubules for Vesicle Transport in Lobster Axons
- 9 January 1987
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 235 (4785) , 220-222
- https://doi.org/10.1126/science.2432661
Abstract
The hypothesis that transported vesicles are preferentially associated with a subclass of microtubules has been tested in lobster axons. A cold block was used to collect moving vesicles in these axons; this treatment caused the vesicles to accumulate in files along some of the microtubules. Quantitative analysis of the number of vesicles associated with microtubule segments indicated that lobster axons have two distinct populations of microtubules--transport microtubules that are the preferred substrates for vesicle transport and architectural microtubules that contribute to axonal structure.This publication has 13 references indexed in Scilit:
- 270K microtubule-associated protein cross-reacting with anti-MAP2 IgG in the crayfish peripheral nerve axon.The Journal of cell biology, 1986
- Cytoskeletal architecture of reactivated crayfish axons, with special reference to crossbridges among microtubules and between microtubules and membrane organellesCell Motility, 1986
- Cross-bridges mediate anterograde and retrograde vesicle transport along microtubules in squid axoplasm.The Journal of cell biology, 1985
- AVEC-DIC and electron microscopic analyses of axonally transported particles in cold-blocked squid giant axonsJournal of Neurocytology, 1985
- Function and Evolution of Neurofilament ProteinsaAnnals of the New York Academy of Sciences, 1985
- Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport.The Journal of cell biology, 1985
- Movement of organelles along filaments dissociated from the axoplasm of the squid giant axonCell, 1985
- Cross-linker system between neurofilaments, microtubules and membranous organelles in frog axons revealed by the quick-freeze, deep-etching methodThe Journal of cell biology, 1982
- The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles.The Journal of cell biology, 1980
- The short term accumulation of axonally transported organelles in the region of localized lesions of single myelinated axonsJournal of Neurocytology, 1980