Replication and inheritance of mitochondrial DNA.

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Abstract
The DNA of Neurospora crassa mitochondria possesses physical continuity throughout several cycles of replication in the course of vegetative growth. The replication of mitochondrial DNA and nuclear DNA are at least in some respects metabolically independent since DNA the precursors for the synthesis of the 2 species are drawn from pools which differ in their rates of turnover and dilution by exogenous sources of nitrogen. The pattern of inheritance of mitochondrial DNA species themselves is predominantly that usually associated with many abnormal mitochondrial phenotypes, namely, uniparental by way of the maternal parent.