HLA and alcoholic cirrhosis
- 1 January 1982
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 19 (1) , 6-10
- https://doi.org/10.1111/j.1399-0039.1982.tb01410.x
Abstract
In 57-patients with alcoholic cirrhosis the frequency of HLA-DR2 was found to be 47.4%, in contrast to 26.1% in 119 normal subjects and 14.0% in 43 cases of autoimmune-type chronic active hepatitis (CAH). The frequencies of HLA-DR3 in the 3 respective groups also differed, being 24.6%, 31.9% and 74.4%. The greatly differing HLA-DR profiles in alcoholic cirrhosis and CAH point to immunogenetic differences in predisposition to these 2 liver diseases.This publication has 9 references indexed in Scilit:
- HLA associations with autoimmune-type chronic active hepatitis: Identification of B8-DRw3 haplotype by family studiesGastroenterology, 1980
- HLA Antigens in Alcoholics, with Special Reference to Alcoholic CirrhosisScandinavian Journal of Gastroenterology, 1980
- HLA-B8, immunoglobulins, and antibody responses in alcohol-related liver disease.Journal of Clinical Pathology, 1980
- Human Leucocyte Antigens in Patients with Alcoholic Liver CirrhosisScandinavian Journal of Gastroenterology, 1980
- Distribution of HLA histocompatibility antigens, ABO blood groups and Rh antigens in alcoholic liver disease.Gut, 1979
- Alcoholic Hyalin Antigen (Ahag) and Antibody (Ahab) in Alcoholic HepatitisGastroenterology, 1977
- Histocompatibility Antigens (HLA): Associations with Immunopathic Diseases and with Responses to Microbial Antigens*Australian and New Zealand Journal of Medicine, 1977
- Histocompatibility Antigens in Chronic Liver DiseaseGastroenterology, 1977
- Genetic Control of Chloroform Toxicity in MiceScience, 1975