Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1′ modifications
- 1 March 1999
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 9 (6) , 835-840
- https://doi.org/10.1016/s0960-894x(99)00096-7
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 ModificationsBioorganic & Medicinal Chemistry Letters, 1998
- RATIONAL DESIGN, SYNTHESIS, AND SERINE PROTEASE INHIBITORY ACTIVITY OF NOVEL P1-ARGININOYL HETEROCYCLESBioorganic & Medicinal Chemistry Letters, 1997
- Contribution of Lysine 60f to S1‘ Specificity of ThrombinBiochemistry, 1997
- New routes to conformationally restricted peptide building blocks: a convenient preparation of bicyclic piperazinone derivativesBioorganic & Medicinal Chemistry Letters, 1996
- Potent Thrombin Inhibitors That Probe the S1‘ Subsite: Tripeptide Transition State Analogues Based on a Heterocycle-Activated Carbonyl GroupJournal of Medicinal Chemistry, 1996
- Direct thrombin inhibitors in cardiovascular medicine.Circulation, 1994
- Hirudin and Hirulog: Advances in antithrombotic therapyPerspectives in Drug Discovery and Design, 1994
- Small-molecule inhibitors of thrombinPerspectives in Drug Discovery and Design, 1994
- Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profileTrends in Pharmacological Sciences, 1993
- The coagulation cascade: initiation, maintenance, and regulationBiochemistry, 1991