5,6- trans -25-Hydroxycholecalciferol: Vitamin D Analog Effective on Intestine of Anephric Rats
- 16 June 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 176 (4040) , 1247-1248
- https://doi.org/10.1126/science.176.4040.1247
Abstract
A new compound, 5,6-trans-25-hydroxycholecalciferol, has been synthesized and tested for its biological activity. Like 1,25-dihydroxycholecalciferol, it stimulates intestinal calcium transport in anephric rats, whereas 25-hydroxycholecalciferol does not. But this analog has little if any activity in stimulating mobilization of calcium from the bone of anephric rats.Keywords
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