Acute respiratory academia

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Abstract
Internal jugular blood gases and electrolytes were correlated with the electroencephalogram [EEG] during acute respiratory acidemia in 10 subjects. CO2 inhalation produced a decrease in pH and increases in O2 tension, O2 saturation, CO2 tension, sodium ionic activity, and potassium ionic activity of cerebral venous blood. Decreases in the pH of the internal jugular blood were closely related to the appearance of EEG slowing, while changes in CO2 tension were not. EEG slowing regularly appeared whenever the pH of internal jugular blood fell below a threshold of 7.087 pH units, regardless of values for CO2 tension. In subjects with occlusion of the middle cerebral artery, EEG slowing appeared at lower levels of CO2 tension in cerebral venous blood than in subjects without it, but the pH threshold remained at the same in the 2 groups.