Antibacterial effects of Cefroxadine, Cephalexin and Cephradine in a new in vitro pharmacokinetic model.
- 1 January 1982
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 35 (7) , 843-849
- https://doi.org/10.7164/antibiotics.35.843
Abstract
A pharmacokinetic model was developed by means of which all possible time courses of the concentrations of antibiotics in the plasma of treated individuals [humans] can be exactly simulated in vitro without diluting the test organism and affecting the growth curves. Equieffective concentrations in the system corresponded to the plasma concentrations in man produced by cefroxadine in a single oral dose of 250 mg and cephalexin and cephradine in a single oral dose of 500 mg.This publication has 7 references indexed in Scilit:
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