Comparison of the inhibition of methotrexate-sensitive and -resistant Lactobacillus casei cell cultures with purified Lactobacillus casei dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted-phenyl)-s-triazines. Use of quantitative structure-activity relationships in making inferences about the mechanism of resistance and the structure of the enzyme in situ compared with the enzyme in vitro
- 1 December 1981
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 24 (12) , 1422-1429
- https://doi.org/10.1021/jm00144a010
Abstract
Note: In lieu of an abstract, this is the article's first page.This publication has 13 references indexed in Scilit:
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