ROLE OF HYPOGLYCEMIA AND CARBON DIOXIDE IN THE REACTION TO STRESS*

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Abstract
The role of hypoglycemia and CO2 in the reaction to hypoxia and cold was investigated in male rats. It was found that hypoxia produces a transient hypoglycemia which reaches a maximum after 4 hours exposure to 20,000 feet. Thereafter the blood sugar returns to normal. Rats exposed to 3[degree] C for 4 hours showed depletion of adrenal ascorbic acid, cholesterol, and eosinopenia. These responses can be partially blocked if the concentration of CO2 in the atmosphere is kept at 5%.