Evaluation of Urinary Elimination of N -Acetyl-β-Glucosaminidase in Healthy Volunteers Treated with Dibekacin or Gentamicin
Open Access
- 1 June 1982
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 21 (6) , 1013-1015
- https://doi.org/10.1128/aac.21.6.1013
Abstract
The urinary excretion of N -acetyl-β-glucosaminidase was studied in healthy subjects during and after treatment with aminoglycosides. In terms of this parameter dibekacin appeared to be less nephrotoxic than gentamicin.This publication has 10 references indexed in Scilit:
- Comparative nephrotoxicities of dibekacin, amikacin, and gentamicin in a rat modelAntimicrobial Agents and Chemotherapy, 1980
- Dibekacin Intrarenal Distribution Characteristics and Renal Cortical Elution Kinetics. Comparison with Gentamicin and TobramycinThe Journal of Clinical Pharmacology, 1980
- The use of urinary N-acetyl-β-glucosaminidase in human renal toxicology I. Partial biochemical characterization and excretion in humans and release from the isolated perfused rat kidneyToxicology and Applied Pharmacology, 1979
- The use of urinary N-acetyl-β-glucosaminidase in human renal toxicology II. Elevation in human excretion after aspirin and sodium salicylateToxicology and Applied Pharmacology, 1979
- Renal damage during treatment with antirheumatic drugs.BMJ, 1978
- In Vitro Comparison of Kanamycin, Kanendomycin, Gentamicin, Amikacin, Sisomicin, and Dibekacin Against 200 Strains of Pseudomonas aeruginosaAntimicrobial Agents and Chemotherapy, 1978
- Antibacterial activity of dibekacin against gentamicin-resistant organisms.1977
- Urinary N-acetyl- beta-D-glucosaminidase activities in patients with renal disease.BMJ, 1975
- Urinary Excretion of Acid Hydrolases in DiseaseScandinavian Journal of Clinical and Laboratory Investigation, 1972
- Studies on glucosaminidase. 2. Substrates for N-acetyl-β-glucosaminidaseBiochemical Journal, 1961