Restricted Feed Consumption and Its Effect on Mammary Gland Growth

Abstract
Individual feed consumption was determined in a group of ovariectomized rats. They were then divided into 2 groups, one restricted to 75% of their individual normal consumption and the other to 50% of normal. During a period of 19 days, the rats were injected with 2 ug EB [estradiol benzoak] plus 6 rag P to stimulate mammary gland growth, then sacrificed and DNA/100 g bw determined. In comparison with a group of 78 full-fed control rats, gland growth was depressed only 3.89%, a nonsignificant amount by 75% of their normal feed intake, and 17.84%, a reduction significant at the 1% level when restricted to 50% of their feed intake.