Increased Activity of Endogenous Endothelin in Patients With Type II Diabetes Mellitus
- 1 October 2002
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Circulation
- Vol. 106 (14) , 1783-1787
- https://doi.org/10.1161/01.cir.0000032260.01569.64
Abstract
Background— Endothelial dysfunction may contribute to the risk of premature atherosclerosis in patients with diabetes. Endothelin (ET-1) may be involved in this process by activating smooth muscle ...Keywords
This publication has 22 references indexed in Scilit:
- Endothelial dysfunction in diabetesBritish Journal of Pharmacology, 2000
- The Effect of an Endothelin-Receptor Antagonist, Bosentan, on Blood Pressure in Patients with Essential HypertensionNew England Journal of Medicine, 1998
- Elevated plasma endothelin‐1 level in streptozotocin‐induced diabetic rats and responsiveness of the mesenteric arterial bed to endothelin‐1British Journal of Pharmacology, 1998
- Contribution of endogenous generation of endothelin-1 to basal vascular toneThe Lancet, 1994
- Insulin influences immunoreactive endothelin release by human vascular smooth muscle cellsMetabolism, 1993
- Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptorLife Sciences, 1992
- Increased Plasma Endothelin in NIDDM Patients With RetinopathyDiabetes Care, 1992
- Circulating and Tissue Endothelin Immunoreactivity in Advanced AtherosclerosisNew England Journal of Medicine, 1991
- Production of endothelin-1 from the mesenteric arteries of streptozotocin-induced diabetic ratsLife Sciences, 1991
- Enhanced secretion of endothelin‐1 by elevated glucose levels from cultured bovine aortic endothelial cellsFEBS Letters, 1990