A neurotoxin N-methyl(R)salsolinol induces apoptotic cell death in differentiated human dopaminergic neuroblastoma SH-SY5Y cells

This publication has 13 references indexed in Scilit:

• A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain
  Neuroscience Letters, 1997
• A dopaminergic neurotoxin, (R)‐N‐methylsalsolinol, increases in parkinsonian cerebrospinal fluid
  Annals of Neurology, 1996
• The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro
  Life Sciences, 1996
• Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies
  Brain Research, 1996
• Synergetic Cytotoxicity of Bleomycin and Polyhydric Alcohols: DNA Strand Breakage Evaluated by "Comet Assay".
  Biological & Pharmaceutical Bulletin, 1996
• Enzymatic oxidation of the dopaminergic neurotoxin, 1 (R), 2(N)-Dimethyl-6,7-Dihydroxy-l,2,3,4-Tetrahydroisoquinoline, into 1,2(N)-Dimethyl-6,7-Dihydroxyisoquinolinium ion
  Life Sciences, 1995
• N-methyl(r)salsolinol produces hydroxyl radicals: Involvement to neurotoxicity
  Free Radical Biology & Medicine, 1995
• Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells
  Neuron, 1993
• Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
  Biochemical and Biophysical Research Communications, 1984
• Alkaloids in mammalian tissues. 2. Synthesis of (+)- and (-)-1-substituted-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines
  Journal of Medicinal Chemistry, 1972