One pot solution synthesis of cyclic oligodeoxyribonucleotides
Open Access
- 1 May 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 18 (9) , 2661-2669
- https://doi.org/10.1093/nar/18.9.2661
Abstract
Several cyclic oligodeoxynucleotides with different base composition and size have been prepared from 5′,3′-unprotected linear precursors, using a bifunctional phosphorylating reagent. The final deprotected ollgomers have been characterized by 1 H- and 31 P-NMR. The present procedure is particularly useful for millimolar scale syntheses.This publication has 8 references indexed in Scilit:
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