Cocarcinogenic and Irritant Factors of Euphorbia Esula L. Latex

Abstract
The latex of « Euphorbia esula » has been found to contain highly skin irritant and inflammatory ingenol-3-Δ2,4,6,8,10 pentene tetradecanoate and another factor, ingenol-3-dodecanoate, which is less irritating but which can be responsible for the cocarcinogenic activity exhibited by the latex preparation in the mice back skin experiment.

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