Effect of Influenza Virus Infection on Allergic Sensitization to Inhaled Antigen in Mice
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 86 (1) , 121-123
- https://doi.org/10.1159/000234617
Abstract
Repeated exposure of healthy mice to an aerosol of ovalbumen (OA) leads to the development of IgE-isotype-specific immunological tolerance. However, when initial OA exposure occurs during the acute phase of influenza infection, tolerance does not occur, and the mice instead develop high titres of OA-specific IgE in response to subsequent challenge with the allergen.Keywords
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