Design and synthesis of a prototypical non-peptidic inhibitor model for the enzme renin
- 1 July 1994
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 4 (14) , 1697-1702
- https://doi.org/10.1016/s0960-894x(00)80364-9
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- Peptidomimetic inhibitors of renin incorporating topographically modified isosteres spanning the P1(→ P3)-P1' sitesBioorganic & Medicinal Chemistry Letters, 1993
- Synthesis of the hydroxyethylene isostere of Leu-ValThe Journal of Organic Chemistry, 1992
- Highly potent, orally active diester macrocyclic human renin inhibitorsJournal of Medicinal Chemistry, 1992
- Synthesis and biological activity of new conformationally restricted analogues of pepstatin*International Journal of Peptide and Protein Research, 1992
- On the Stereochemical Divergence in the Conjugate Addition of Lithium Dimethylcuprate/Trimethylsilyl Chloride to γ-Alkoxy and γ-Ureido α,β-Unsaturated EstersSynthesis, 1991
- Diastereoselective Synthesis of the Hydroxyethylene Dipeptide Isostere of Leu–ValChemistry Letters, 1989
- Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analog inhibitors containing a novel analog of statineJournal of Medicinal Chemistry, 1985
- Effects of a specific and long-acting renin inhibitor in the marmoset.Hypertension, 1985
- Rat angiotensinogen and des(angiotensin I)angiotensinogen: purification, characterization, and partial sequencingBiochemistry, 1981
- The amino terminal amino acid sequence of human angiotensinogenBiochemical and Biophysical Research Communications, 1981