Abstract
Upon prolonged incubation of two auxotrophic mutants from Streptomyces griseoflavus 142 plated together on minimal medium, heterocaryotic colonies producing only parental type conidia were formed. In addition, from the mixed culture of two double auxotrophs on a medium supplemented with limited amounts of nutrients, stable recombinant-type conidia were recovered at relatively high frequencies. According to these observations, it is suggested that genetic recombination occurs in heterocaryotic mycelial growth antecedent to conidiation. However, complete synapsis appears to be doubtful because of the unbalanced patterns of recombinant recovery.

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