Mapping the mutation causing the X-linked lymphoproliferative syndrome in relation to restriction fragment length polymorphisms on Xq

Abstract
The X-linked lymphoproliferative syndrome (XLP) results in fatal infectious mononucleosis, hypogammaglobulinemia, and malignant lymphoma. The mutation has been mapped relative to several restriction fragment length polymorphism (RFLP) markers in the X121-Xq27 vicinity. The DXS37 locus was found to be near both the DXS42 and XLP loci.