Molecular dimensions of gastrointestinal tumors: Some thoughts for digestion
- 19 September 2003
- journal article
- review article
- Published by Wiley in American Journal of Medical Genetics Part A
- Vol. 122A (4) , 303-314
- https://doi.org/10.1002/ajmg.a.20473
Abstract
Topics discussed here include PTEN mutations and colonic polyps; WNT signaling, APC, β‐catenin, and gastrointestinal neoplasms; mismatch‐repair genes (MLH1, MSH2, PMS1, MSH6) and hereditary nonpolyposis colorectal cancer; MYH mutations and autosomal recessive colorectal tumors; STK11 mutations and Peutz‐Jeghers syndrome; TGFβ and gastrointestinal cancer; BMPR1A mutations and juvenile polyposis; FGF/FGFR alterations in gastrointestinal neoplasms; PTCH mutations and gastrointestinal neoplasms; RUNX3 expression and gastric cancer; role of mucins in gastric carcinogenesis; KIT, PDGFRα, and gastrointestinal stromal tumors; intestinal neurofibromatosis; and gastrointestinal tumors in other disorders.Keywords
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