Lupus Nephritis: Varying Complement-Fixing Properties of Immunoglobulin G Antibodies to Antigens of Cell Nuclei

30 August 1968

journal article
other
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 161 (3844) , 904-906
https://doi.org/10.1126/science.161.3844.904

Abstract

Relative complement-fixing activity of antibodies to nuclear antigens, including DNA, were determined in serums of 15 patients with, and 65 patients without, active lupus nephritis, by comparing titers obtained in two methods. High complement-fixing activity of antibody was found in the nephritis group and low activity in the others. Results with immunoglobulin G fractions were similar.

Keywords

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