THE TREATMENT OF GOLD DERMATITIDES

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Abstract
In the past ten years much has been done with gold therapy in the treatment of rheumatoid arthritis. The work of Freyberg1 and his associates on the metabolism of gold and numerous reports on chrysotherapy by other workers2 have simplified the problem of gold administration to a certain extent. However, the use of gold compounds in the treatment of rheumatoid arthritis remains on an empiric basis and is still far from universally accepted.3 Toxic reactions to gold have been a serious deterrent to its use in therapy. Even under the most careful clinical supervision, the administration of gold to human subjects continues to be attended with definite hazards. The occurrence of certain manifestations of toxicity— notably the dermatitides—cannot be predicted by any known clinical or laboratory method.4 It is therefore important to control these reactions rapidly once they develop. In certain patients we have been able