CYTOCHEMICAL MECHANISMS OF PENICILLIN ACTION VIII

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Abstract
Double staining of penicillin assay plates with triphenyltetrazolium chloride and with trypan blue provides further evidence to support the conclusion that the inhibition of enzyme systems involved in H transfer and in the dephosphorylation of complex ribonucleates is fundamentally involved in the action of penicillin on Gram-positive organisms. The use of the same technics suggests that the action of polymyxin on the Gram-negative Escherichia coli is effected through essentially similar mechanisms.