Factors affecting the systemic antifungal activity of some chemically related compounds

Abstract
Some phenols, phenolic glycosides and derivatives of sulphanilic acid were tested for direct (in vitro) and systemic activity against some rust and mildew fungi. Results against Uromyces fabae are quoted. Some of the highly substituted phenols were toxic to U. fabae, but there was little systemic activity in broad beans and wheat shoots with phenols or phenolic glycosides. Although 4‐aminobenzenesulphonamides and 4‐aminobenzenesulphonylureas were relatively inactive in vitro, they showed appreciable systemic activity. Modification of the structure of compounds to confer solubility in water did not necessarily improve systemic activity.