Carbamate Insecticides: Synergism by Organothiocyanates1

Abstract
Isotronyl thiocyanoacetate and related thiocyanates were shown to be highly synergistic when used in combination with several insecticidal carbamates against the house fly, Musca domestica L. Synergism comparable to that obtained with commercially available methylenedioxyphenyl synergists was demonstrated against susceptible and carbamate-resistant flies. Experiments with C14-labeled carbamates showed that the synergism involved inhibition of the biochemical detoxication of the carbamate within the body of the fly.