Characterization of the antibodies detected by the microscopic agglutination test for bovine leptospirosis
- 1 December 1974
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 73 (3) , 425-432
- https://doi.org/10.1017/s0022172400042789
Abstract
Summary: The nature of the antibodies detectable by the microscopic agglutination test for bovine leptospirosis was examined. Density gradient ultracentrifugation, gel filtration and disulphide-bond-reduction experiments indicated that antileptospiral agglutinating activity was present in both IgM and IgG immunoglobulin fractions. This was confirmed by selective precipitation of specific antibody classes and ion-exchange chromatography.Keywords
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