Evidence that AphB, Essential for the Virulence of Vibrio vulnificus , Is a Global Regulator
- 15 May 2008
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 190 (10) , 3768-3773
- https://doi.org/10.1128/jb.00058-08
Abstract
The Vibrio vulnificus aphB mutant was significantly less virulent than the wild type and was impaired in motility and adherence to host cells. Microarray analysis revealed that AphB of V. vulnificus (AphB Vv ) influences the expression of over 10% of the V. vulnificus genome. The combined results indicated that AphB Vv is a global regulator contributing to the pathogenesis of V. vulnificus .Keywords
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