THE EFFECT OF INSULIN ON CARDIAC AND LIVER GLYCOGEN

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Abstract
Rats were injected intravenously with glucose, with or without insulin. Cardiac glycogen was increased by glucose but not further increased by the addition of insulin. For such glucose injected animals, the liver glycogen was lowered by insulin and progressively so as the dose was increased; the effect occurs even during hyperglycemia; it is not mediated by the adrenal. Possible explanations are discussed.

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