Ethylenediamine–oligo DNA hybrid as sequence-selective artificial ribonuclease
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 1,p. 77-78
- https://doi.org/10.1039/c39950000077
Abstract
A hybrid of ethylenediamine and a DNA oligomer selectively hydrolyses linear RNA at the phosphodiester linkage which is adjacent to the sequence complementary to the DNA.Keywords
This publication has 20 references indexed in Scilit:
- Synthesis of oligonucleotides containing N2-(5-carboxypentyl)-2′-deoxyguanosine and 5-[2-(4′-methyl-2,2′-dipyrid-4-yl-carboxamido)ethylthio]-2′-deoxyuridineTetrahedron Letters, 1993
- Recognition of tertiary structure in tRNAs by Rh(phen)2phi3+, a new reagent for RNA structure-function mappingBiochemistry, 1992
- Synthesis and characterization of nucleoside peptides: toward chemical ribonucleases. 1The Journal of Organic Chemistry, 1990
- Hydrolysis of RNA by transition metal complexesJournal of the American Chemical Society, 1990
- Probing Nucleic Acids with Transition Metal ComplexesPublished by Wiley ,1990
- Efficient cleavage of adenylyl(3′-5′)adenosine by triethylenetetraminecobalt(III)Journal of the Chemical Society, Chemical Communications, 1990
- Defining the Inside and Outside of a Catalytic RNA MoleculeScience, 1989
- Probing the environment of lanthanide binding sites in yeast tRNAPhe by specific metal‐ion‐promoted cleavagesEuropean Journal of Biochemistry, 1989
- Scission of RNA by the chemical nuclease of 1,10-phenanthroline-eopper ion: preference for single-stranded loopsNucleic Acids Research, 1989
- Basic polypeptides accelerate the hydrolysis of ribonucleic acidsJournal of the American Chemical Society, 1988