The effect of diphenylhydantoin on nerve conduction velocity

Publisher Website
Google Scholar
Abstract
Nerve conduction velocity studies were performed on the median and ulnar motor and sensory nerves in the upper extremities, both in patients receiving diphenylhydantoin and in those in a matched normal control group. No significant differences were found between the two groups. This would militate against an axonal effect of diphenylhydantoin in the peripheral nerves of the upper extremities in the dosages used and would favor the synaptic theory of action.