Advances in the Diagnosis of Renal Candidiasis

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Abstract
Candiduria may signify benign saprophytic colonization or true infection of the [human] urinary tract. Histological studies of 64 suspect cases of renal candidiasis, 20 of them positive, suggest that a Candida colony count of 10,000-15,000/ml. or more in a catheterized specimen is a useful cut-off point between infection and colonization. One to 3 Candida/high power field in an uncentrifuged urine specimen equated with a colony count of 10,000-15,000 Candida/ml. Colony counts were diagnostically invalid in the presence of an indwelling Foley catheter. Other diagnostic aids included positive serum precipitin tests (83%) and positive blood cultures (47%).