Polymorphic variants in human chromosome 15

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Abstract
We found eight polymorphic variants in human chromosome 15 using Q, C, Q‐C and Ag‐NOR staining methods. These variants included brightly or dully fluorescent pericentric segments and satellites, giant satellites, increased amounts of short arm heterochromatin (ph+) and darkly (C band‐positive) or lightly (C band‐negative) Giemsa‐stained pericentric Q‐negative segments. These staining properties indicated that the entire short arm of 15 contained at least four distinct chromatin segments: Q‐negative centrometric heterochromatin, a Q‐vriable distal segment, a Q‐negative satellite stalk, and Q‐variable satellites, in that order, from proximal to distal ends. The Brd U‐Hoechst 33258‐stained R bands (RBH) and high resolution G subbands were also studied for karyologic characterization of chromosome 15. Most of these variants were reported also in 13, but insufficiently documented in other D and G chromosomes. Together with polymorphic pericentric fluorochromes seen in 3 and 4, Yq, and nonpathogenic t(D;Yq), the pattern of these variants can be used as karyologic fingerprints for identification of each individual and his or her cell explants both in vivo and in vitro.