Pattern Formation inside Bacteria: Fluctuations due to the Low Copy Number of Proteins
- 27 March 2003
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 90 (12) , 128102
- https://doi.org/10.1103/physrevlett.90.128102
Abstract
We examine fluctuation effects due to the low copy number of proteins involved in pattern-forming dynamics within a bacterium. We focus on a stochastic model of the oscillating MinCDE protein system regulating accurate cell division in E. coli. We find that, for some parameter regions, the protein concentrations are low enough that fluctuations are essential for the generation of patterns. We also examine the role of fluctuations in constraining protein concentration levels.Keywords
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