Zinc is required for structural stability of the C‐terminus of archaeal translation initiation factor aIF2β
- 26 March 2002
- journal article
- Published by Wiley in FEBS Letters
- Vol. 517 (1-3) , 155-158
- https://doi.org/10.1016/s0014-5793(02)02610-8
Abstract
AIF2beta is an archaeal homolog of eukaryotic translation factor eIF2beta necessary for translation initiation and involved in recognition of the initiation codon. In the present study, we demonstrate for the first time zinc binding to the C2-C2 zinc finger at the C-terminus of aIF2beta. Nuclear magnetic resonance backbone assignments were also determined and the secondary structural elements identified.Keywords
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