The Major Histocompatibility Complex of Rhesus Monkeys IX. Current Concepts of Serology and Genetics of Ia Antigensa

Publisher Website
Google Scholar
Abstract
Eleven Ia [immune response-associated] or B[bone marrow-derived]-cell specificities of rhesus monkeys were serologically identified. They are probably all controlled by the RhLA complex, but, according to results of a large population and family study, only 5 or 6 can be placed in a segregant series, designated as Ia1. Data from recombinant offspring in 2 rhesus families place the Ia1 locus in the close vicinity of the D or major MLC [mixed lymphocyte culture] locus within RhLA. The genetic control of the Ia antigens not defined by the Ia1 locus has not yet been clarified.