Comparison of two methods to assess the intake of flavouring substances
- 1 November 1999
- journal article
- research article
- Published by Taylor & Francis in Food Additives & Contaminants
- Vol. 16 (11) , 481-495
- https://doi.org/10.1080/026520399283777
Abstract
It is important to assess the intake of flavouring substances in order to be confident that exposure to the substance from its intended use presents no significant risk. A number of methods exist to estimate intake of food ingredients. Two such methods, one using a detailed dietary analysis based on food consumption and composition and one using 10 times the annual volume of use on a per capita basis (per capita x 10), were compared for their precision and practicality in assessing the intake of 10 flavouring substances. The detailed dietary analysis method of determining exposure resulted in good estimates of the distribution of intakes across the population, as well as patterns of intake of individuals. This method is both expensive and labour intensive. The per capita x 10 method yields results that, compared with those obtained by detailed dietary analysis, tend consistently to overstate exposure. Thus, this method is a conservative and practical approach to assessing exposure to flavouring substances and other food ingredients.Keywords
This publication has 9 references indexed in Scilit:
- A procedure for the safety evaluation of flavouring substancesFood and Chemical Toxicology, 1999
- Principles for the Safety Evaluation of Flavouring SubstancesFood and Chemical Toxicology, 1998
- Stepwise Approaches for Estimating the Intakes of Chemicals in FoodRegulatory Toxicology and Pharmacology, 1997
- Correlation of structural class with no-observed-effect levels: A proposal for establishing a threshold of concernFood and Chemical Toxicology, 1996
- FEMA GRAS - A GRAS Assessment Program for Flavor IngredientsRegulatory Toxicology and Pharmacology, 1995
- GRAS evaluation of flavoring substances by the Expert Panel of FEMARegulatory Toxicology and Pharmacology, 1991
- Safety assurance margins for food additives currently in useRegulatory Toxicology and Pharmacology, 1987
- FDA's priority-based assessment of food additives I. Preliminary resultsRegulatory Toxicology and Pharmacology, 1984
- Criteria employed by the expert panel of fema for the gras evaluation of flavouring substancesFood and Cosmetics Toxicology, 1977