Structural diversity of the major surface antigen of Plasmodium falciparum merozoites.
Open Access
- 1 March 1986
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 6 (3) , 964-968
- https://doi.org/10.1128/mcb.6.3.964
Abstract
The structures of the major merozoite surface antigen of Plasmodium falciparum and the gene encoding it were indistinguishable for the Wellcome strain and the Thai clone T9/94 but different for clones T9/96, T9/98, and T9/101. The central portion of the gene is subject to the greatest variation in structure. The protein from all five lines was found to be posttranslationally modified by covalent addition of both carbohydrate and fatty acid.This publication has 24 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- Polymorphism of a high molecular weight schizont antigen of the human malaria parasite Plasmodium falciparum.The Journal of Experimental Medicine, 1985
- Major surface antigen gene of a human malaria parasite cloned and expressed in bacteriaNature, 1984
- The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor.The Journal of Experimental Medicine, 1984
- Expression of cloned cDNA for a major surface antigen of Plasmodium falciparum merozoitesFEBS Letters, 1984
- Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody.The Journal of Experimental Medicine, 1982
- Antigenic Diversity in the Human Malaria Parasite Plasmodium falciparumScience, 1982
- ProteolipidsAnnual Review of Biochemistry, 1981
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970