A single-strip mini-paper chromatographic method for rapid purity-control of 99mTc-labeled radiopharmaceuticals
- 1 November 1986
- journal article
- research article
- Published by Springer Nature in European Journal of Nuclear Medicine and Molecular Imaging
- Vol. 12 (8) , 390-393
- https://doi.org/10.1007/bf00252196
Abstract
A single-strip miniaturized paper chromatographic method (Mini-PC) was developed using 80%–90% acetone solvent for rapid purity-control of 99mTc-radiopharmaceuticals. Routine 99mTc-radiopharmaceuticals (eight kinds of “kit” made agents) and diluted agents (in which radiochemical impurities might be formed) were analyzed by Mini-PC and other methods. This showed that, compared with the other methods, the Mini-PC technique is useful for the simple and rapid routine analysis of radiochemical impurities of “kit” made 99mTc-radiopharmaceuticals.Keywords
This publication has 9 references indexed in Scilit:
- [Rapid quality-control procedures for 99mTc radiopharmaceuticals].1984
- [Current topics in radiopharmaceuticals in Japan (V). Quality of "kit"-made radiopharmaceuticals (2)--Radiochemical purity of 99mTc radiopharmaceuticals].1984
- Rapid miniaturized chromatography for Tc-99m IDA agents: Comparison with gel chromatographyEuropean Journal of Nuclear Medicine and Molecular Imaging, 1982
- RADIOCHEMICAL ANALYSIS OF TC-99M HUMAN-SERUM ALBUMIN WITH HIGH-PRESSURE LIQUID-CHROMATOGRAPHY - CONCISE COMMUNICATION1982
- Quality control studies of 99mTc-labeled radiopharmaceuticals by high-performance liquid chromatographyThe International Journal of Applied Radiation and Isotopes, 1981
- Quality control of 99mTc-radiopharmaceuticalsEuropean Journal of Nuclear Medicine and Molecular Imaging, 1980
- Quality control of colloid and particulate 99mTc-labeled radiopharmaceuticalsEuropean Journal of Nuclear Medicine and Molecular Imaging, 1979
- RAPID MINIATURIZED CHROMATOGRAPHIC QUALITY-CONTROL PROCEDURES FOR TC-99M RADIOPHARMACEUTICALS1977
- RAPID-DETERMINATION OF OXIDATION-STATE OF UNBOUND TC-99M AND LABELING YIELD IN TC-99M LABELED RADIOPHARMACEUTICALS1976