Calcitonin gene‐related peptide (CGRP) and transcutaneous electrical nerve stimulation (TENS) increase cutaneous blood flow in a musculocutaneous flap in the rat

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Abstract
The effect of blood flow on transcutaneous electrical nerve stimulation (TENS) and injection of calcitonin gene-related peptide (CGRP) was studied in a musculocutaneous flap of the rat, using laser Doppler flowmetry. The circulatory border w-as estimated bcfore and after treatment. It was shown that repeated treatments with TENS gradually increased the blood flow, moving the circulatory border distalll- more than 100% after three treatments. Injection of NaCl into the dorsal central vein of the flap resulted in no increase in blood flow, whereas CGRP 10-10 m increased the blood flow, so that the circulator) border moved distally 70% and 60%, rcspcctivcly.