Metabolism of Steroids II. Half-Life of Various Steroids in Dogs.

Publisher Website
Google Scholar
Abstract
The half-life of exogenous cortisol, cortisone, corticosterone and [DELTA] 1-corti-sol was studied in dogs. Individual dogs tend to remove exogenous cortisol at a characteristic rate, with some difference in this rate among different animals. Compared with the half-life for cortisol that for cortisone was much the same; in contrast [DELTA]1-cortisol half-life was considerably longer and corticosterone half-life considerably shorter. In dogs the half-life of exogenous steroids was shorter than in man, except for corticosterone where they were equal.