Toxicology of antisense therapeutics

This publication has 98 references indexed in Scilit:

• Ribozymes: A modern tool in medicine
  Journal of Biomedical Science, 2003
• Killing the messenger: short RNAs that silence gene expression
  Nature Reviews Molecular Cell Biology, 2003
• Efficiency of Antisense Oligonucleotide Drug Discovery
  Antisense and Nucleic Acid Drug Development, 2002
• Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS
  American Journal of Ophthalmology, 2002
• A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with aids11InternetAdvance publication at ajo.com Feb 8, 2002.Financial disclosures and conflict of interest statements are listed at the end of the article.Reprint requests to René Lanz, PhD, Novartis Ophthalmics AG, Grenzstrasse 10, CH-8180 Bülach, Switzerland; fax: (41) 1-862-0762; e-mail: rene.lanz@pharma.novartis.comCorrespondence to Stephen L. Hutcherson, MBA, Cyclix Ltd. LLC, 11851 Rexmoor Drive, Richmond, VA 23236; fax: (804) 897-9544; e-mail: cyclix@comcast.net
  American Journal of Ophthalmology, 2002
• Potent Gene-Specific Inhibitory Properties of Mixed-Backbone Antisense Oligonucleotides Comprised of 2‘-Deoxy-2‘-fluoro-d-arabinose and 2‘-Deoxyribose Nucleotides^,
  Biochemistry, 2002
• Bolus Intravenous Injection of Phosphorothioate Oligonucleotides Causes Hypotension by Acting as α1-Adrenergic Receptor Antagonists
  Toxicology and Applied Pharmacology, 1999
• CYTOCHROME P450-BASED CANCER GENE THERAPY: RECENT ADVANCES AND FUTURE PROSPECTS
  Drug Metabolism Reviews, 1999
• PAAn-1b and PAAn-E: Two Phosphorothioate Antisense Oligodeoxynucleotides Inhibit Human Aromatase Gene Expression
  Biochemical and Biophysical Research Communications, 1998
• The Multiple Inhibitory Mechanisms of GEM 91®, agagAntisense Phosphorothioate Oligonucleotide, for Human Immunodeficiency Virus Type 1
  AIDS Research and Human Retroviruses, 1997