Indirect Effects of Localized Deuteron Irradiation of the Rat

Open Access
Publisher Website
Google Scholar
Abstract
A cylindrical 5/8 in. diam. beam of 190 Mev deuterons was used to obtain selective irradiation of head, liver, adrenal, intestine and hind-quarters regions in the intact unanesthetized rat. The wts. of spleen, thymus, adrenals, kidneys and testis were detd. in animals sacrificed at 1, 3, 6 and 9 days after doses of 3564 rep to these regions. Changes in thymus, spleen and adrenal wts. in the several exptl. groups were those characteristic of pituitary-adrenal stimulation, and occurred only when irradiation imposed severe stress upon the animal as indicated by the appearance of gross symptoms of illness and body wt. loss. Changes in kidney and testis wts. roughly paralleled body wt. loss.
Keywords

This publication has 4 references indexed in Scilit: