Activity of 17β-hydroxysteroid dehydrogenase in various tissues of human skin
- 1 December 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 105 (6) , 693-699
- https://doi.org/10.1111/j.1365-2133.1981.tb00980.x
Abstract
The activity of 17.beta.-hydroxysteroid dehydrogenase (17.beta.-HSD) was assayed in various tissues microdissected from the freeze-dried human skin of 14 subjects. The apocrine sweat gland, sebaceous gland and hair follicle possessed a high activity of 17.beta.-HSD. Enzyme activity was negligible in the epidermis, except that the scalp epidermis showed much the same activity as the hair follicle. The dermis showed variable activity because of contamination with other components.This publication has 12 references indexed in Scilit:
- DISTRIBUTION OF ANDROGEN METABOLIZING ENZYMES IN ISOLATED TISSUES OF HUMAN FOREHEAD AND AXILLARY SKINJournal of Endocrinology, 1978
- A study of the in vitro metabolism of androgens by human scalp and pubic skinBritish Journal of Dermatology, 1977
- METABOLISM OF ANDROGENS IN VITRO BY HUMAN FOETAL SKINJournal of Endocrinology, 1976
- Regulation of Human Hair Growth by Steroid Hormones. II. Androstenedione Metabolism in Isolated HairsJournal of Clinical Endocrinology & Metabolism, 1974
- METABOLISM OF ANDROGENS IN VITRO BY HUMAN FACIAL AND AXILLARY SKINJournal of Endocrinology, 1973
- Metabolism of androgens by isolated human hair folliclesJournal of Steroid Biochemistry, 1972
- Conversion of Testosterone-1,23H to Androstenedione-3H in the Isolated Hair Follicle of ManJournal of Clinical Endocrinology & Metabolism, 1972
- 17β-Hydroxysteroid Dehydrogenase of Rat SkinPublished by Elsevier ,1972
- SURVEY OF THE DISTRIBUTION OF STEROID DEHYDROGENASES IN SEBACEOUS GLANDS OF HUMAN SKINBritish Journal of Dermatology, 1970
- In vitro metabolism of testosterone-4-14C and Δ4-androstene-3,17-dione-414C in human skinBiochemistry, 1968