Sarcomatous Type of Malignant Mesothelioma

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Abstract
Thirteen malignant mesotheliomas of a sarcomatous type were studied by light microscopy and 10 were studied by EM. The histologic patterns varied from tumor to tumor, often resembling other soft tissue sarcomas. EM observation showed most of the tumors to be composed of primitive cells. Despite their mesenchymal character, many tumors contained foci of rudimentary epithelial differentiation. Both histologic types of malignant mesothelioma, the epithelial and the sarcomatous, apparently originate from the same precursor cell at various points of its differentiation and reflect the range of maturation from the mesenchymal reserve cell to the epithelial mesothelial cell.

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