Non-Suitability of Levator Ani Method as an Index of Anabolic Effect of Steroids

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Abstract
Injection of androgens such as testosterone propionate or Norethandrolone in normal and castrated male rats promotes growth of the m. levator ani (l.a.) even on protein-free diets. Based on these and other experiments, it is assumed that the growth of this muscle is a sex-linked function. It is, therefore, concluded that the hormone-induced growth of this muscle is not an appropriate index for the general "myotropic", i.e., anabolic effects of steroid compounds. On repletion of protein depleted normal rats the weight of the m.la. was significantly higher on high fat than on the high carbohydrate diet.